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Maria Stella Graziani

Deputy Director
Martina Zaninotto

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Ferruccio Ceriotti
Davide Giavarina
Bruna Lo Sasso
Giampaolo Merlini
Martina Montagnana
Andrea Mosca
Paola Pezzati
Rossella Tomaiuolo
Matteo Vidali

International Advisory Board Khosrow Adeli Canada
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Marcello Ciaccio Italy
Eleftherios Diamandis Canada
Philippe Gillery France
Kjell Grankvist Sweden
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Magdalena Krintus Poland
Giuseppe Lippi Italy
☩Howard Morris Australia
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☩Jill Tate Australia
Tommaso Trenti Italy
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Maria Willrich USA
Paul Yip Canada


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Biomedia srl
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Responsible Editor
Giuseppe Agosta

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Arianna Lucini Paioni
Biomedia srl
Via L. Temolo 4, 20126 Milano
Tel. 0245498282
email: biochimica.clinica@sibioc.it



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BC: Articoli scritti da L. Paparo

Meccanismi epigenetici nella patogenesi dell’allergia al latte vaccino
Epigenetics and cow’s milk allergy: implication for pathogenesis
<p>Cows&rsquo; milk allergy (CMA) is one of the most&nbsp;frequent allergies in child, often occurring quite soon after birth. Recent years have been featured by an increasing&nbsp;prevalence of CMA that can often be the first appearance of the so-called &ldquo;atopic march&rdquo;. Typically, CMA is featured&nbsp;by immunoglobulin E (IgE)-mediated reactions; however, the pathogenetic basis of IgE-mediated CMA is not yet&nbsp;completely understood. Recent evidences suggest that epigenetic factors, such as DNA methylation and regulatory&nbsp;non-coding RNAs could play a role in allergic diseases, including CMA. Here, we review the state of the art regarding&nbsp;the involvement of some epigenetic modifications in allergic diseases, and especially in CMA. We describe that&nbsp;epigenetic derived molecules, in addition to be pathogenetic factors contributing to typical CMA allergic phenomena,&nbsp;could also serve to produce molecules which may act as novel, specific and easily accessible biomarkers for CMA&nbsp;diagnosis and monitoring.</p>
Biochimica Clinica ; 42(2) 103-111
Rassegne - Reviews