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BC: Articoli scritti da E. Fiorio

Il ruolo di CA 15-3 nel monitoraggio della terapia nel carcinoma mammario metastatico
Role of CA15-3 to guide therapy in metastatic breast cancer
C. Cocco  |  B. Caruso  |  E. Fiorio  | 
<p>The National Academy of Clinical Biochemistry&nbsp;states that cancer antigen 15-3 (CA15-3) in combination with imaging and clinical examinations can be used for&nbsp;therapeutic monitoring in patients with advanced breast cancer. In a 62 year old patient with a 2 year history of&nbsp;invasive ductal breast carcinoma and bone metastasis, treated with an aromatase inhibitor, the imaging showed bone&nbsp;marrow infiltration and liver metastasis. The oncologist planned a close monitoring of the disease and the patient has&nbsp;been followed for two years by CA15-3 every month and imaging when necessary. It has been observed that the&nbsp;clinician modified the therapy on the basis of the CA15-3 values during two phases of apparent stability of the&nbsp;disease. This case report shows that the CA15-3 has contributed to a large extent to stop ineffective treatments and&nbsp;has effectively helped the clinician in selecting the most appropriate treatment options. However, it is to be noted that&nbsp;the monthly request of the marker is not appropriate.</p>
Biochimica Clinica ; 40(2) e08-e11
Casi clinici - Case report
Armonizzazione in Medicina di Laboratorio
Harmonization in Laboratory Medicine
Biochimica Clinica ; 39(6) 546-547
Editoriale - Editorial