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Maria Stella Graziani

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Martina Zaninotto

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Bruna Lo Sasso
Giampaolo Merlini
Martina Montagnana
Andrea Mosca
Paola Pezzati
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Matteo Vidali

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Giuseppe Agosta

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Arianna Lucini Paioni
Biomedia srl
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email: biochimica.clinica@sibioc.it



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BC: Articoli scritti da C. Bovo

Intervalli di riferimento dell’esame emocromocitometrico nel sangue di cordone ombelicale
Reference intervals for cell counts of umbilical cord blood
F. Dima  |  M. Montagnana  |  R. Raffaelli  |  S. Cascella  |  C. Bovo  |  M. Franchi  |  G. Lippi  | 
<p>The umbilical cord blood is useful for assessing the&nbsp;health status in newborns. A limited number of studies evaluated the reference values of peripheral blood cell count&nbsp;and little information is available on the number of stem cells in umbilical cord blood. This study aimed to define&nbsp;reference intervals for hematological parameters in umbilical cord blood. 257 umbilical cord blood samples were&nbsp;obtained from apparently healthy infants with gestational age &gt;37 weeks, uncomplicated pregnancy, birth weight&nbsp;&gt;2500 g and umbilical arterial pH &gt;7.0. The analysis was performed within 3 h from collection using the hematology&nbsp;analyzer Sysmex XN-1000. Reference values were derived with a non-parametric approach, by following the CLSI&nbsp;document EP28&ndash;A3c. A statistically significant difference between genders was observed for erythrocytes,&nbsp;hemoglobin, hematocrit and red blood cell distribution width, these parameters being significantly higher in males&nbsp;than in females. Results from this study may be seen as a useful guide for neonatologists to evaluate the newborn&nbsp;status and for hematologists to evaluate the quality of collected blood.</p>
Biochimica Clinica ; 40(3) 204-207
Contributi scientifici - Scientific Papers
 
Impatto epidemiologico della patologia ischemica del miocardio in Italia
Epidemiologic burden of ischemic heart disease in Italy
G. Lippi  |  C. Mattiuzzi  |  C. Bovo  |  G. Cervellin  | 
<p>Background: this article provides an updated overview on the current epidemiologic burden of ischemic heart disease (IHD) in Italy.<br />Methods: an electronic search was carried out in the Global Health Data Exchange (GHDx) registry, using the keyword &ldquo;ischemic heart disease&rdquo;, for retrieving recent information (year 2017) on incidence, prevalence, health loss (expressed as disability-adjusted life year, DALYs) and mortality of IHD in Italy.<br />Results: the cumulative incidence, prevalence and mortality of IHD in Italy are 0.38%, 3.47% and 0.16% respectively, whilst the impact on health loss is 1.11 million DALYs (6.73% of total DALYs). Incidence, prevalence and DALYs are higher in men than in women, whilst mortality is only marginally higher in males. Overall, IHD is the first cause of death in Italy (15.5% of all deaths). During the last three decades the incidence has constantly increased (+30%), whilst DALYs have declined in both sexes by ~30%. Mortality for IHD steadily decreased in men (-13%), whilst it remained almost unchanged in women. The curve of incidence of IHD in Italy peaks between 60-84 years in men and between 75-94 years in women. The mortality curve of IHD in Italy peaks in both sexes between 85-94 years. Hypertension, hypercholesterolemia and diabetes are the leading risk factors for IHD in Italy.<br />Conclusions: IHD still poses a substantial clinical, social and economic burden in Italy.</p>
Biochimica Clinica ; 17(1)
Contributi Scientifici - Scientific Papers